17 Results for "

Withania somnifera

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "Withania somnifera" in MCE Product Catalog:

13
Withaferin A
Withaferin A
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13 Publications Verification
Cat. No.: HY-N2065
CAS No.: 5119-48-2
Category:  

other families Withania somnifera Plants Solanaceae Disease Research Fields Inflammation/Immunology Steroids

Target:  

NF-κB Ferroptosis

Withaferin A is a steroidal lactone isolated from Withania somnifera, inhibits NF-kB activation and targets vimentin, with potent antiinflammatory and anticancer activities. Withaferin A is an inhibitor of endothelial protein C receptor (EPCR) shedding.
1
Withanone
Withanone
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1 Cited Publications
Cat. No.: HY-129692
CAS No.: 27570-38-3
Purity:  93.06%
Category:  

Withania somnifera Plants Solanaceae Steroids

Target:  

iGluR

Withanone is an active ingredient from the roots of Withania somnifera and a GRP75 inhibitor. Withanone has multifunctional neuroprotective effects in alleviating cognitive dysfunction. In neuron-like cells, Withanone can inhibit NMDA-induced excitotoxicity. Withanone can inhibit white adipose tissue browning by blocking the formation of the GRP75-ANT2-UCP1 complex, thereby alleviating cancer-related cachexia. Withanone can be used in the research of tumors and nervous system diseases .
1
2,3-Didehydrosomnifericin
2,3-Didehydrosomnifericin
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1 Cited Publications
Cat. No.: HY-N5069
CAS No.: 173614-88-5
Category:  

other families Other Diseases Plants Disease Research Fields Steroids

Target:  

Bacterial

2,3-Didehydrosomnifericin is one of withanolides found in Withania somnifera .
Sominone
Sominone
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Cat. No.: HY-N10889
CAS No.: 98569-64-3
Category:  

Withania somnifera Plants Solanaceae Steroids

Target:  

Drug Metabolite RET

Sominone is the active metabolite of Withanoside IV (HY-N8693). Sominone enhances neuronal morphological plasticity by activating the RET pathway. Sominone can also induce axon/dendrite regeneration and synaptic reconstruction, thereby improving spatial memory. Sominone can be used in the research of neurodegenerative diseases such as Alzheimer's disease .
Withaferin A (Standard)
Withaferin A (Standard)
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Cat. No.: HY-N2065R
CAS No.: 5119-48-2
Category:  

other families Withania somnifera Plants Solanaceae Steroids

Target:  

Reference Standards NF-κB Ferroptosis

Withaferin A (Standard) is the analytical standard of Withaferin A. This product is intended for research and analytical applications. Withaferin A is a steroidal lactone isolated from Withania somnifera, inhibits NF-kB activation and targets vimentin, with potent antiinflammatory and anticancer activities. Withaferin A is an inhibitor of endothelial protein C receptor (EPCR) shedding.
Dihydrowithaferin A
Dihydrowithaferin A
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Cat. No.: HY-N5120
CAS No.: 5589-41-3
Synonyms: 2,3-Dihydrowithaferin A
Category:  

Withania somnifera Plants Solanaceae Disease Research Fields Cancer Steroids

Target:  

Cholinesterase (ChE)

Dihydrowithaferin A (2, 3-dihydrowithaferin A) is a withanolide isolated from Withania somnifera. Dihydrowithaferin A is active against acetylcholinesterase (AChE) .
3β-Methoxy-2,3-dihydrowithaferin A
3β-Methoxy-2,3-dihydrowithaferin A
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Cat. No.: HY-N5131
CAS No.: 73365-94-3
Synonyms: Quresimin A
Category:  

other families Other Diseases Plants Disease Research Fields Steroids

Target:  

Others

3β-Methoxy-2,3-dihydrowithaferin A is one of withanolides found in Withania somnifera .
Withasomniferolide A
Withasomniferolide A
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Cat. No.: HY-N10884
CAS No.: 2365386-74-7
Category:  

Withania somnifera Plants Solanaceae Steroids

Target:  

Others

Withasomniferolide A is a withanolide, isolated from a GABAA receptor positive activator methanol extract of the roots of Withania somnifera .
Withasomniferolide B
Withasomniferolide B
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Cat. No.: HY-N10887
CAS No.: 2365386-75-8
Category:  

Withania somnifera Plants Solanaceae Steroids

Target:  

GABA Receptor

Withasomniferolide B is a withanolide. Withasomniferolide B can be isolated from a GABAA receptor positive activator methanol extract of the roots of Withania somnifera .
4-Dehydrowithaferin A
4-Dehydrowithaferin A
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Cat. No.: HY-138146
CAS No.: 6850-30-2
Synonyms: 4-oxo Withaferin A
Category:  

Quinones Withania somnifera Benzene Quinones Plants Solanaceae Disease Research Fields Cancer

Target:  

Drug Derivative

4-Dehydrowithaferin A is the analogue of withaferin A. Withaferin A is a withanolide isolated from Withania somnifera. 4-Dehydrowithaferin A has the potential for the research of multiple myeloma .
Withania somnifera extract
Withania somnifera extract
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Cat. No.: HY-N18728
CAS No.: 90147-43-6
Category:  

Extract

Target:  

Others

Withania somnifera extract, derived from the roots and leaves of the South African ashwagandha (Withania somnifera), contains a variety of bioactive components, including solanolactones (such as solanolactone A, solanolactone D, and solanine A), solanosin (such as solanosin IV and solanosin VI), alkaloids (such as isopretiline and anaflin), β-sitosterol, benzoic acid, and tropane alkaloids. Withania somnifera extract has been extensively studied for its benefits in stress management, anxiety relief, improved physical function, and overall health.
6α-Chloro-5β-hydroxywithaferin A
6α-Chloro-5β-hydroxywithaferin A
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Cat. No.: HY-N5113
CAS No.: 52329-20-1
Category:  

Other Diseases Withania somnifera Plants Solanaceae Disease Research Fields Steroids

Target:  

Bacterial

6α-Chloro-5β-hydroxywithaferin A is a withanolide that can be isolated from W. somnifera. W. somnifera has antioxidant, anti-inflammatory, immunomodulatory, anticarcinogenic, antibacterial antiparkinsonism and antistress properties .
Kaempferol-3-O-robinoside-7-O-glucoside
Kaempferol-3-O-robinoside-7-O-glucoside
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Cat. No.: HY-N11702
CAS No.: 114924-89-9
Category:  

Flavonoids Flavones Withania somnifera Plants Solanaceae

Target:  

Others

Kaempferol-3-O-robinoside-7-Oglucoside is a double-chain flavonol triglycoside can be extracted from Withania somnifera .
Withanoside V (Standard)
Withanoside V (Standard)
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Cat. No.: HY-N8671R
CAS No.: 256520-90-8
Category:  

Withania somnifera Plants Solanaceae Steroids

Target:  

Reference Standards Others

Withanoside V (Standard) is the analytical standard of Withanoside V. This product is intended for research and analytical applications. Withanoside V, a withanolide glycoside, exhibits inhibitory activity for tachyphylaxis to Clonidine in isolated guinea-pig ileum .
Viscosalactone B
Viscosalactone B
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Cat. No.: HY-N10949
CAS No.: 76938-46-0
Category:  

Withania somnifera Plants Solanaceae Steroids

Target:  

Others

Viscosalactone B is a withanolide found in Withania somnifera. Viscosalactone B shows potent inhibitory activities to NCI-H460, HCT-116, MCF-7 and SF-268 cancer cells with IC50 values of 0.32, 0.47, 0.4 and 0.45 μg/mL. Viscosalactone B can be used for the research of cancer .
Withanone (Standard)
Withanone (Standard)
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Cat. No.: HY-129692R
CAS No.: 27570-38-3
Category:  

Withania somnifera Plants Solanaceae Steroids

Target:  

Reference Standards iGluR

Withanone (Standard) is the analytical standard of Withanone (HY-129692). This product is intended for research and analytical applications. Withanone is an active ingredient from the roots of Withania somnifera and a GRP75 inhibitor. Withanone has multifunctional neuroprotective effects in alleviating cognitive dysfunction. In neuron-like cells, Withanone can inhibit NMDA-induced excitotoxicity. Withanone can inhibit white adipose tissue browning by blocking the formation of the GRP75-ANT2-UCP1 complex, thereby alleviating cancer-related cachexia. Withanone can be used in the research of tumors and nervous system diseases .
Withanolide D
Withanolide D
0 Images
Cat. No.: HY-N17756
CAS No.: 30655-48-2
Category:  

Microorganisms Ketones, Aldehydes, Acids

Target:  

HSP

Withanolide D (Compound 2) is a steroidal ester found in Withania somnifera (L.) Dunal, with anticancer activity. Withanolide D can activate the heat-shock factor 1 (HSF1)-dependent stress response. Withanolide D can be used for the research of cancer such as lymphoma .
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Assay Types